Qnexa, a diet drug for weight loss and obesity has been rejected after lots of R&D and I’m sure big hopes by the many people who struggle with obesity as well as the drug maker that this would make it to market after promising studies showed a substantial benefit in weight loss.
The drug combines two different drugs, one a stimulant which suppresses appetite and the other a medication that is meant to stop seizures (anti convulsant). The combination had high hopes for helping those that were having a hard time losing weight, but ultimately an FDA panel rejected it and recommended it not be approved to go to market in the weight loss industry.
The reason? Well, even though a pretty remarkable benefit was shown by those that were taking it versus those that were not, the risks outweigh the benefit and when that happens, as expected, the FDA has the right to reject it.
It actually was among several other hopeful diet drugs that were being presented to the FDA for possible approval, so we’ll see if any of the others will get through the fairly rigorous and sometimes considered ambiguous process of approval.
I must admit I find it odd that this drug was rejected and yet very serious medical pain relievers that are causing thousand of people to become almost instant addicts were approved without much ado.
However, I must say that the potential side effects are not good for Qnexa. Some of the ones that were identified were suicidal thoughts, increased heart rate and potential birth defects in women who bore children while on the drug or that had been on the drug (it is not clear exactly which one).
The primary reason behind the disapproval was the concern over safety and the lack of enough data to back up that it was safe enough to introduce to the general public. However, the studies showing it’s effectiveness impressed everyone, pretty much showing that it may have been the most effective weight loss drug on the market had it been approved.